HGNC approved symbol | PRKCB |
HGNC ID | HGNC:9395 |
HGNC approved name | protein kinase C, beta |
Entrez gene ID | GeneID:5579 (SSTAR profile) |
UniProt AC (human) | P05771 |
UniProt ID (human) | KPCB_HUMAN |
Pfam domains | C1_1 PF00130 (37-86, 102-153) C2 PF00168 (172-277) Pkinase PF00069 (344-596) Pkinase_C PF00433 (621-662) |
MGI symbol | Prkcb |
MGI ID | MGI:97596 |
UniProt AC (mouse) | P68404 |
UniProt ID (mouse) | KPCB_MOUSE |
HGNC gene family tag | # |
HGNC gene family description | # |
Function | Histone modification write |
Modification | Histone methylation |
PMID for information on function | PMID:20228790 |
Protein complex | # |
Target molecule | histone |
Target entity | H3T6 |
Product | H3T6ph |
PMID for information on target | PMID:20228790 |
Comment | Phosphorylation of histone H3 at threonine 6 (H3T6) by protein kinase C beta I (PKCbeta(I), also known as PRKCbeta) is the key event that prevents LSD1 from demethylating H3K4 during AR-dependent gene activation. |
Status of entry | # |
Expression range: | 0.0 to 812.67 |
Mean expression: | 55.31 ± 109.44 |
Median expression: | 0.29 |