HGNC approved symbol | PKN1 |
HGNC ID | HGNC:9405 |
HGNC approved name | protein kinase N1 |
Entrez gene ID | GeneID:5585 (SSTAR profile) |
UniProt AC (human) | Q16512 |
UniProt ID (human) | PKN1_HUMAN |
Pfam domains | HR1 PF02185 (38-98, 127-194, 214-278) Pkinase PF00069 (616-874) Pkinase_C PF00433 (895-937) |
MGI symbol | Pkn1 |
MGI ID | MGI:108022 |
UniProt AC (mouse) | P70268 |
UniProt ID (mouse) | PKN1_MOUSE |
HGNC gene family tag | # |
HGNC gene family description | # |
Function | Histone modification write |
Modification | Histone phosphorylation |
PMID for information on function | PMID:18066052 |
Protein complex | # |
Target molecule | histone |
Target entity | H3T11 |
Product | H3T11ph |
PMID for information on target | PMID:18066052 |
Comment | Protein-kinase-C-related kinase 1 (PRK1=PKN1) phosphorylates histone H3 at threonine 11 (H3T11) upon ligand-dependent recruitment to androgen receptor target genes. |
Status of entry | # |
Expression range: | 0.0 to 189.56 |
Mean expression: | 30.56 ± 20.09 |
Median expression: | 26.44 |