HGNC approved symbol | ARID1B |
HGNC ID | HGNC:18040 |
HGNC approved name | AT rich interactive domain 1B (SWI1-like) |
Entrez gene ID | GeneID:57492 (SSTAR profile) |
UniProt AC (human) | Q8NFD5 |
UniProt ID (human) | ARI1B_HUMAN |
Pfam domains | ARID PF01388 (1137-1223) BAF250_C PF12031 (2006-2266) |
MGI symbol | Arid1b |
MGI ID | MGI:1926129 |
UniProt AC (mouse) | # |
UniProt ID (mouse) | # |
HGNC gene family tag | ARID |
HGNC gene family description | # |
Function | Histone modification write |
Modification | Histone ubiquitination |
PMID for information on function | PMID:20086098 |
Protein complex | BAF, nBAF, npBAF, PBAF, SWI/SNF-like_EPAFa, SWI/SNF-like EPAFB, SWI/SNF BRM-BRG1 |
Target molecule | histone, DNA |
Target entity | H2BK120, DNA motif |
Product | # |
PMID for information on target | PMID:20086098 |
Comment | The characteristic member of human SWI/SNF-A is BAF250/ARID1, of which there are two isoforms, BAF250a/ARID1a and BAF250b/ARID1b. The immunopurified BAF250b E3 ubiquitin ligase was found to target histone H2B at lysine 120 for monoubiquitination in vitro. |
Status of entry | # |
Expression range: | 0.0 to 132.84 |
Mean expression: | 23.87 ± 16.33 |
Median expression: | 19.15 |