HGNC approved symbol | MTA3 |
HGNC ID | HGNC:23784 |
HGNC approved name | metastasis associated 1 family, member 3 |
Entrez gene ID | GeneID:57504 (SSTAR profile) |
UniProt AC (human) | Q9BTC8 |
UniProt ID (human) | MTA3_HUMAN |
Pfam domains | BAH PF01426 (4-145) ELM2 PF01448 (150-202) Myb_DNA-binding PF00249 (269-314) GATA PF00320 (379-415) MTA_R1 PF17226 (462-537) |
MGI symbol | Mta3 |
MGI ID | MGI:2151172 |
UniProt AC (mouse) | Q924K8 |
UniProt ID (mouse) | MTA3_MOUSE |
HGNC gene family tag | GATAD |
HGNC gene family description | GATA zinc finger domain containing |
Function | Chromatin remodeling cofactor |
Modification | # |
PMID for information on function | PMID:12705869 |
Protein complex | NuRD |
Target molecule | chromatin |
Target entity | # |
Product | # |
PMID for information on target | PMID:12705869 |
Comment | The product of human MTA3 is an estrogen-dependent component of the Mi-2/NuRD transcriptional corepressor in breast epithelial cells. MTA3 constitutes a key component of an estrogen-dependent pathway regulating growth and differentiation. |
Status of entry | # |
Expression range: | 0.0 to 218.5 |
Mean expression: | 19.14 ± 17.0 |
Median expression: | 16.26 |