HGNC approved symbol | RARA |
HGNC ID | HGNC:9864 |
HGNC approved name | retinoic acid receptor, alpha |
Entrez gene ID | GeneID:5914 (SSTAR profile) |
UniProt AC (human) | P10276 |
UniProt ID (human) | RARA_HUMAN |
Pfam domains | zf-C4 PF00105 (87-155) Hormone_recep PF00104 (227-399) |
MGI symbol | Rara |
MGI ID | MGI:97856 |
UniProt AC (mouse) | P11416 |
UniProt ID (mouse) | RARA_MOUSE |
HGNC gene family tag | NR |
HGNC gene family description | Nuclear hormone receptors |
Function | Histone modification write cofactor, TF |
Modification | Histone methylation, TF activator, TF repressor |
PMID for information on function | PMID:19377461 |
Protein complex | # |
Target molecule | histone |
Target entity | H3K4 |
HOCOMOCO TFBS model | |
Product | H3K4me, H3K4me2 |
PMID for information on target | PMID:19377461 |
Comment | MLL5 is biochemically identified in a GlcNAcylation-dependent multi-subunit complex associating with nuclear retinoic acid receptor RARalpha (also known as RARA), serving as a mono- and di-methyl transferase to H3K4. |
Status of entry | # |
Expression range: | 3.67 to 957.82 |
Mean expression: | 65.13 ± 93.36 |
Median expression: | 38.57 |