HGNC approved symbol | KDM5A |
HGNC ID | HGNC:9886 |
HGNC approved name | lysine (K)-specific demethylase 5A |
Entrez gene ID | GeneID:5927 (SSTAR profile) |
UniProt AC (human) | P29375 |
UniProt ID (human) | KDM5A_HUMAN |
Pfam domains | JmjN PF02375 (20-53) ARID PF01388 (86-170) PHD PF00628 (296-340, 1164-1215) JmjC PF02373 (470-586) KDM5_C-hel PF21323 (590-644) zf-C5HC2 PF02928 (676-728) PLU-1 PF08429 (741-1070) |
MGI symbol | Kdm5a |
MGI ID | MGI:2136980 |
UniProt AC (mouse) | Q3UXZ9 |
UniProt ID (mouse) | KDM5A_MOUSE |
HGNC gene family tag | KDM, PHF |
HGNC gene family description | Chromatin-modifying enzymes / K-demethylases, Zinc fingers, PHD-type |
Function | Histone modification erase |
Modification | Histone methylation |
PMID for information on function | PMID:17320163 |
Protein complex | # |
Target molecule | histone |
Target entity | H3K4me3 |
Product | H3K4 |
PMID for information on target | PMID:17320163 |
Comment | The retinoblastoma binding protein RBP2 =KDM5A is an H3K4 demethylase. |
Status of entry | # |
Expression range: | 0.0 to 137.07 |
Mean expression: | 19.97 ± 14.23 |
Median expression: | 16.08 |