Gene info
| HGNC approved symbol | REST |
| HGNC ID | HGNC:9966 |
| HGNC approved name | RE1-silencing transcription factor |
| Entrez gene ID | GeneID:5978 (SSTAR profile) |
| UniProt AC (human) | Q13127 |
| UniProt ID (human) | REST_HUMAN |
| Pfam domains | zf-C2H2 PF00096 (304-326) |
| MGI symbol | Rest |
| MGI ID | MGI:104897 |
| UniProt AC (mouse) | Q8VIG1 |
| UniProt ID (mouse) | REST_MOUSE |
| HGNC gene family tag | # |
| HGNC gene family description | # |
| Function | Histone modification erase cofactor, TF |
| Modification | Histone acetylation, TF activator, TF repressor |
| PMID for information on function | PMID:12399542 |
| Protein complex | # |
| Target molecule | DNA |
| Target entity | DNA motif |
| HOCOMOCO TFBS model | |
| Product | # |
| PMID for information on target | PMID:12399542 |
| Comment | REST/NRSF can mediate repression, in part, through the association of its NH2-terminal repression domain with the mSin3/histone deacethylase 1,2 (HDAC1,2) complex. |
| Status of entry | # |
Expression statistics
| Expression range: | 0.0 to 191.69 |
| Mean expression: | 32.78 ± 23.16 |
| Median expression: | 26.39 |