| HGNC approved symbol | ACTB |
| HGNC ID | HGNC:132 |
| HGNC approved name | actin, beta |
| Entrez gene ID | GeneID:60
(SSTAR profile) |
| UniProt AC (human) | P60709 |
| UniProt ID (human) | ACTB_HUMAN |
| Pfam domains | Actin PF00022 (4-375) |
| MGI symbol | Actb |
| MGI ID | MGI:87904 |
| UniProt AC (mouse) | P60710 |
| UniProt ID (mouse) | ACTB_MOUSE |
| HGNC gene family tag | # |
| HGNC gene family description | # |
| Function | Chromatin remodeling cofactor |
| Modification | # |
| PMID for information on function | PMID:10966108 |
| Protein complex | BAF, nBAF, npBAF, PBAF, SWI/SNF-like EPAFB, bBAF, SWI/SNF BRM-BRG1, NuA4, NuA4-related complex |
| Target molecule | chromatin |
| Target entity | # |
| Product | # |
| PMID for information on target | PMID:10966108 |
| Comment | β-actin=ACTB and actin-related proteins appear to have weak ATPase activities, which contribute ∼1% of the total activity in the BAF remodeling complex (Zhao et al. 1998). Results of experiments using the actin monomer sequestering product latrunculin B suggest that β-actin and BAF53 are required for stimulation of the ATPase activity of the BAF complex by chromatin |
| Status of entry | # |