HGNC approved symbol | ATXN7 |
HGNC ID | HGNC:10560 |
HGNC approved name | ataxin 7 |
Entrez gene ID | GeneID:6314 (SSTAR profile) |
UniProt AC (human) | O15265 |
UniProt ID (human) | ATX7_HUMAN |
Pfam domains | SCA7 PF08313 (332-395) |
MGI symbol | Atxn7 |
MGI ID | MGI:2179277 |
UniProt AC (mouse) | Q8R4I1 |
UniProt ID (mouse) | ATX7_MOUSE |
HGNC gene family tag | ATXN |
HGNC gene family description | Ataxins |
Function | Histone modification write cofactor |
Modification | Histone acetylation |
PMID for information on function | PMID:16494529 |
Protein complex | SAGA |
Target molecule | histone |
Target entity | # |
Product | # |
PMID for information on target | PMID:16494529 |
Comment | Ataxin-7 (ATXN7) is a subunit of the GCN5 histone acetyltransferase–containing coactivator complexes TFTC/STAGA. TFTC/STAGA complexes purified from SCA7 mice have normal TRRAP, GCN5, TAF12, and SPT3 levels and that their histone or nucleosomal acetylation activities are unaffected. |
Status of entry | # |