HGNC approved symbol | SMYD3 |
HGNC ID | HGNC:15513 |
HGNC approved name | SET and MYND domain containing 3 |
Entrez gene ID | GeneID:64754 (SSTAR profile) |
UniProt AC (human) | Q9H7B4 |
UniProt ID (human) | SMYD3_HUMAN |
Pfam domains | SET PF00856 (15-239) zf-MYND PF01753 (49-87) |
MGI symbol | Smyd3 |
MGI ID | MGI:1916976 |
UniProt AC (mouse) | Q9CWR2 |
UniProt ID (mouse) | SMYD3_MOUSE |
HGNC gene family tag | ZMYND, KMT |
HGNC gene family description | Zinc fingers, MYND-type, Chromatin-modifying enzymes / K-methyltransferases |
Function | Histone modification write |
Modification | Histone methylation |
PMID for information on function | PMID:15235609 |
Protein complex | # |
Target molecule | histone |
Target entity | H3K4, H3K5 |
Product | H3K4me2, H3K4me3, H3K5me2, H3K5me3 |
PMID for information on target | PMID:15235609 |
Comment | The SET domain of SMYD3 shows histone H3-lysine 4 (H3-K4)-specific methyltransferase activity, which is enhanced in the presence of the heat-shock protein HSP90A. |
Status of entry | # |
Expression range: | 0.0 to 494.98 |
Mean expression: | 21.74 ± 29.6 |
Median expression: | 17.05 |