HGNC approved symbol | SMARCC2 |
HGNC ID | HGNC:11105 |
HGNC approved name | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 |
Entrez gene ID | GeneID:6601 (SSTAR profile) |
UniProt AC (human) | Q8TAQ2 |
UniProt ID (human) | SMRC2_HUMAN |
Pfam domains | SWIRM-assoc_2 PF16496 (5-137) SWIRM PF04433 (434-512) Myb_DNA-binding PF00249 (600-642) SWIRM-assoc_3 PF16498 (683-748) SWIRM-assoc_1 PF16495 (864-945) |
MGI symbol | Smarcc2 |
MGI ID | MGI:1915344 |
UniProt AC (mouse) | Q6PDG5 |
UniProt ID (mouse) | SMRC2_MOUSE |
HGNC gene family tag | # |
HGNC gene family description | # |
Function | Chromatin remodeling cofactor |
Modification | # |
PMID for information on function | PMID:10078207 |
Protein complex | BAF, nBAF, npBAF, PBAF, SWI/SNF_Brg1(I), SWI/SNF_Brg1(II), SWI/SNF_Brm, SWI/SNF-like_EPAFa, WINAC, SWI/SNF-like EPAFB, bBAF, SWI/SNF BRM-BRG1 |
Target molecule | chromatin |
Target entity | # |
Product | # |
PMID for information on target | PMID:10078207 |
Comment | The addition of INI1, BAF155, and BAF170 =SMARCC2 to BRG1 increases remodeling activity to a level comparable to that of the whole hSWI/SNF complex. |
Status of entry | # |
Expression range: | 2.45 to 91.63 |
Mean expression: | 26.08 ± 12.65 |
Median expression: | 23.54 |