HGNC approved symbol | HIRA |
HGNC ID | HGNC:4916 |
HGNC approved name | histone cell cycle regulator |
Entrez gene ID | GeneID:7290 (SSTAR profile) |
UniProt AC (human) | P54198 |
UniProt ID (human) | HIRA_HUMAN |
Pfam domains | WD40 PF00400 (9-44, 64-97, 122-159, 166-201) Hira PF07569 (764-962) |
MGI symbol | Hira |
MGI ID | MGI:99430 |
UniProt AC (mouse) | Q61666 |
UniProt ID (mouse) | HIRA_MOUSE |
HGNC gene family tag | WDR |
HGNC gene family description | WD repeat domain containing |
Function | Histone modification read |
Modification | # |
PMID for information on function | PMID:9710638 |
Protein complex | # |
Target molecule | histone |
Target entity | H2B, H4 |
Product | # |
PMID for information on target | PMID:9710638 |
Comment | HIRA interacts with core histone H4. H2B- and H4-binding domains are overlapping but distinguishable in the carboxy-terminal region of HIRA, and the region for HIRA interaction has been mapped to the amino-terminal tail of H2B and the second alpha helix of H4. |
Status of entry | # |
Expression range: | 11.52 to 143.92 |
Mean expression: | 41.82 ± 15.16 |
Median expression: | 39.95 |