Gene info
| HGNC approved symbol | VDR |
| HGNC ID | HGNC:12679 |
| HGNC approved name | vitamin D (1,25- dihydroxyvitamin D3) receptor |
| Entrez gene ID | GeneID:7421 (SSTAR profile) |
| UniProt AC (human) | P11473 |
| UniProt ID (human) | VDR_HUMAN |
| Pfam domains | zf-C4 PF00105 (23-91) Hormone_recep PF00104 (227-403) |
| MGI symbol | Vdr |
| MGI ID | MGI:103076 |
| UniProt AC (mouse) | P48281 |
| UniProt ID (mouse) | VDR_MOUSE |
| HGNC gene family tag | NR |
| HGNC gene family description | Nuclear hormone receptors |
| Function | Chromatin remodeling cofactor, TF |
| Modification | # |
| PMID for information on function | PMID:16252006 |
| Protein complex | # |
| Target molecule | histone |
| Target entity | H2BK12ac, H3K14ac, H4K16ac |
| HOCOMOCO TFBS model | |
| Product | # |
| PMID for information on target | PMID:16252006 |
| Comment | WINAC associates with chromatin through a physical interaction between the WSTF bromodomain and acetylated histones, which appears to be indispensable for VDR/promoter association for ligand-induced transrepression of 1α(OH)ase gene expression. |
| Status of entry | # |
Expression statistics
| Expression range: | 0.0 to 209.4 |
| Mean expression: | 13.43 ± 27.09 |
| Median expression: | 5.28 |