HGNC approved symbol | PRDM2 |
HGNC ID | HGNC:9347 |
HGNC approved name | PR domain containing 2, with ZNF domain |
Entrez gene ID | GeneID:7799 (SSTAR profile) |
UniProt AC (human) | Q13029 |
UniProt ID (human) | PRDM2_HUMAN |
Pfam domains | PRDM2_PR PF21549 (30-144) zf-C2H2 PF00096 (360-382, 390-412) zf-C2H2_6 PF13912 (483-506, 1455-1475) |
MGI symbol | Prdm2 |
MGI ID | MGI:107628 |
UniProt AC (mouse) | # |
UniProt ID (mouse) | # |
HGNC gene family tag | KMT |
HGNC gene family description | Chromatin-modifying enzymes / K-methyltransferases |
Function | Histone modification write |
Modification | Histone methylation |
PMID for information on function | PMID:20084102 |
Protein complex | # |
Target molecule | histone |
Target entity | H3K9 |
Product | H3K9me |
PMID for information on target | PMID:20084102 |
Comment | The structures of the catalytic domains of GLP, G9a, Suv39H2 and PRDM2, four of the eight known human H3K9 methyltransferases in their apo conformation or in complex with the methyl donating cofactor, and peptide substrates. |
Status of entry | # |
Expression range: | 4.55 to 505.02 |
Mean expression: | 45.46 ± 49.38 |
Median expression: | 26.7 |