HGNC approved symbol | PRR14 |
HGNC ID | HGNC:28458 |
HGNC approved name | proline rich 14 |
Entrez gene ID | GeneID:78994 (SSTAR profile) |
UniProt AC (human) | Q9BWN1 |
UniProt ID (human) | PRR14_HUMAN |
Pfam domains | Tantalus PF15386 (463-519) |
MGI symbol | Prr14 |
MGI ID | MGI:2384565 |
UniProt AC (mouse) | Q7TPN9 |
UniProt ID (mouse) | PRR14_MOUSE |
HGNC gene family tag | # |
HGNC gene family description | # |
Function | Histone modification write |
Modification | Histone phosphorylation |
PMID for information on function | PMID:24209742 |
Protein complex | # |
Target molecule | histone |
Target entity | H3K9me2, H3K9me3 |
Product | # |
PMID for information on target | # |
Comment | Binds to H3K9me2/3 through interaction with HP1, and not by direct interaction. PRR14 is incorporated rapidly into chromatin through HP1 binding, tethering heterochromatin to nuclear lamina. |
Status of entry | # |