HGNC approved symbol | SUV39H2 |
HGNC ID | HGNC:17287 |
HGNC approved name | suppressor of variegation 3-9 homolog 2 (Drosophila) |
Entrez gene ID | GeneID:79723 (SSTAR profile) |
UniProt AC (human) | Q9H5I1 |
UniProt ID (human) | SUV92_HUMAN |
Pfam domains | Chromo PF00385 (47-95) Pre-SET PF05033 (149-242) SET PF00856 (262-373) |
MGI symbol | Suv39h2 |
MGI ID | MGI:1890396 |
UniProt AC (mouse) | Q9EQQ0 |
UniProt ID (mouse) | SUV92_MOUSE |
HGNC gene family tag | KMT |
HGNC gene family description | Chromatin-modifying enzymes / K-methyltransferases |
Function | Histone modification write |
Modification | Histone methylation |
PMID for information on function | PMID:15107829 |
Protein complex | # |
Target molecule | histone |
Target entity | H3K9me1 |
Product | H3K9me3 |
PMID for information on target | PMID:15107829 |
Comment | Suv39h proteins are histone methyltransferases that methylate histone H3 on lysine 9, resulting in transcriptional repression or silencing of target genes. |
Status of entry | # |
Expression range: | 0.0 to 78.37 |
Mean expression: | 13.48 ± 12.46 |
Median expression: | 9.04 |