HGNC approved symbol | TET1 |
HGNC ID | HGNC:29484 |
HGNC approved name | tet methylcytosine dioxygenase 1 |
Entrez gene ID | GeneID:80312 (SSTAR profile) |
UniProt AC (human) | Q8NFU7 |
UniProt ID (human) | TET1_HUMAN |
Pfam domains | zf-CXXC PF02008 (585-625) Tet_JBP PF12851 (1580-2051) |
MGI symbol | Tet1 |
MGI ID | MGI:1098693 |
UniProt AC (mouse) | Q3URK3 |
UniProt ID (mouse) | TET1_MOUSE |
HGNC gene family tag | # |
HGNC gene family description | # |
Function | DNA modification |
Modification | DNA hydroxymethylation |
PMID for information on function | PMID:23222540 |
Protein complex | # |
Target molecule | DNA |
Target entity | mC |
Product | hmC |
PMID for information on target | PMID:23222540 |
Comment | Ten eleven translocation (TET) enzymes, including TET1, TET2 and TET3, convert 5-methylcytosine to 5-hydroxymethylcytosine and regulate gene transcription. |
Status of entry | # |
Expression range: | 0.0 to 274.12 |
Mean expression: | 4.36 ± 13.69 |
Median expression: | 1.24 |