HGNC approved symbol | EPC1 |
HGNC ID | HGNC:19876 |
HGNC approved name | enhancer of polycomb homolog 1 (Drosophila) |
Entrez gene ID | GeneID:80314 (SSTAR profile) |
UniProt AC (human) | Q9H2F5 |
UniProt ID (human) | EPC1_HUMAN |
Pfam domains | EPL1 PF10513 (6-148) E_Pc_C PF06752 (581-836) |
MGI symbol | Epc1 |
MGI ID | MGI:1278322 |
UniProt AC (mouse) | Q8C9X6 |
UniProt ID (mouse) | EPC1_MOUSE |
HGNC gene family tag | # |
HGNC gene family description | # |
Function | Polycomb group (PcG) protein |
Modification | # |
PMID for information on function | PMID:14966270 |
Protein complex | NuA4, Piccolo_NuA4, NuA4-related complex |
Target molecule | histone |
Target entity | # |
Product | # |
PMID for information on target | PMID:14966270 |
Comment | The Enhancer of Polycomb homology domain of human EPC1, like Epl1 in yeast (7), is a conserved functional key for histone acetylation since it bridges the MYST HAT with the ING protein to enable potent nucleosome histone acetyltransferase activity. |
Status of entry | # |
Expression range: | 1.42 to 293.1 |
Mean expression: | 37.76 ± 45.28 |
Median expression: | 20.84 |