HGNC approved symbol | GSG2 |
HGNC ID | HGNC:19682 |
HGNC approved name | germ cell associated 2 (haspin) |
Entrez gene ID | GeneID:83903 (SSTAR profile) |
UniProt AC (human) | Q8TF76 |
UniProt ID (human) | HASP_HUMAN |
Pfam domains | Haspin_kinase PF12330 (420-783) |
MGI symbol | Gsg2 |
MGI ID | MGI:1194498 |
UniProt AC (mouse) | Q9Z0R0 |
UniProt ID (mouse) | HASP_MOUSE |
HGNC gene family tag | # |
HGNC gene family description | # |
Function | Histone modification write |
Modification | Histone phosphorylation |
PMID for information on function | PMID:20705812 |
Protein complex | # |
Target molecule | histone |
Target entity | H3T3 |
Product | H3T3ph |
PMID for information on target | PMID:20705812 |
Comment | Phosphorylation of histone H3 threonine 3 (H3T3ph) by Haspin=GSG2 is necessary for CPC accumulation at centromeres and that CPC subunit Survivin binds directly to H3T3ph. |
Status of entry | # |