| HGNC approved symbol | SPOP |
| HGNC ID | HGNC:11254 |
| HGNC approved name | speckle-type POZ protein |
| Entrez gene ID | GeneID:8405 (SSTAR profile) |
| UniProt AC (human) | O43791 |
| UniProt ID (human) | SPOP_HUMAN |
| Pfam domains | domain PF22486 (33-161) BTB PF00651 (191-296) |
| MGI symbol | Spop |
| MGI ID | MGI:1343085 |
| UniProt AC (mouse) | Q6ZWS8 |
| UniProt ID (mouse) | SPOP_MOUSE |
| HGNC gene family tag | BTBD |
| HGNC gene family description | BTB/POZ domain containing |
| Function | Histone modification write |
| Modification | Histone ubiquitination |
| PMID for information on function | PMID:15897469 |
| Protein complex | # |
| Target molecule | histone |
| Target entity | MacroH2A1 |
| Product | MacroH2A1ub |
| PMID for information on target | PMID:15897469 |
| Comment | The E3 ubiquitin ligase consisting of SPOP and CULLIN3 is able to ubiquitinate the Polycomb group protein BMI1 and the variant histone MACROH2A. |
| Status of entry | # |
| Expression range: | 4.51 to 110.87 |
| Mean expression: | 32.28 ± 14.98 |
| Median expression: | 29.17 |