HGNC approved symbol | USP44 |
HGNC ID | HGNC:20064 |
HGNC approved name | ubiquitin specific peptidase 44 |
Entrez gene ID | GeneID:84101 (SSTAR profile) |
UniProt AC (human) | Q9H0E7 |
UniProt ID (human) | UBP44_HUMAN |
Pfam domains | zf-UBP PF02148 (28-91) UCH PF00443 (273-675) |
MGI symbol | Usp44 |
MGI ID | MGI:3045318 |
UniProt AC (mouse) | Q8C2S0 |
UniProt ID (mouse) | UBP44_MOUSE |
HGNC gene family tag | USP |
HGNC gene family description | Ubiquitin-specific peptidases |
Function | Histone modification erase |
Modification | Histone ubiquitination |
PMID for information on function | PMID:22681888 |
Protein complex | # |
Target molecule | histone |
Target entity | H2Bub1 |
Product | H2B |
PMID for information on target | PMID:22681888 |
Comment | USP44 is most likely an H2Bub1-specific DUB, whose downregulation during ESC differentiation contributes to increased H2Bub1 levels. |
Status of entry | # |
Expression range: | 0.0 to 115.39 |
Mean expression: | 1.65 ± 8.6 |
Median expression: | 0.0 |