| HGNC approved symbol | KAT8 |
| HGNC ID | HGNC:17933 |
| HGNC approved name | K(lysine) acetyltransferase 8 |
| Entrez gene ID | GeneID:84148 (SSTAR profile) |
| UniProt AC (human) | Q9H7Z6 |
| UniProt ID (human) | KAT8_HUMAN |
| Pfam domains | Tudor-knot PF11717 (54-110) zf-MYST PF17772 (176-230) MOZ_SAS PF01853 (235-412) |
| MGI symbol | Kat8 |
| MGI ID | MGI:1915023 |
| UniProt AC (mouse) | Q9D1P2 |
| UniProt ID (mouse) | KAT8_MOUSE |
| HGNC gene family tag | KAT, ZC2HC |
| HGNC gene family description | Chromatin-modifying enzymes / K-acetyltransferases, Zinc fingers, C2HC-type containing |
| Function | Histone modification write |
| Modification | Histone acetylation |
| PMID for information on function | PMID:10786633 |
| Protein complex | NSL, CHD8, MLL2/3, COMPASS-like MLL1,2, MLL4/WBP7 |
| Target molecule | histone |
| Target entity | H2A, H3, H4 |
| Product | H2Aac, H3ac, H4ac |
| PMID for information on target | PMID:10786633 |
| Comment | A recombinant C-terminal portion of hMOF=KAT8 has histone acetyltransferase activity directed toward histones H3, H2A and H4, a specificity characteristic of other MYST family histone acetyltransferases. |
| Status of entry | # |
| Expression range: | 11.76 to 200.56 |
| Mean expression: | 48.67 ± 24.84 |
| Median expression: | 43.37 |