| HGNC approved symbol | CUL1 |
| HGNC ID | HGNC:2551 |
| HGNC approved name | cullin 1 |
| Entrez gene ID | GeneID:8454 (SSTAR profile) |
| UniProt AC (human) | Q13616 |
| UniProt ID (human) | CUL1_HUMAN |
| Pfam domains | Cullin PF00888 (20-662) Cullin_Nedd8 PF10557 (706-766) |
| MGI symbol | Cul1 |
| MGI ID | MGI:1349658 |
| UniProt AC (mouse) | Q9WTX6 |
| UniProt ID (mouse) | CUL1_MOUSE |
| HGNC gene family tag | # |
| HGNC gene family description | # |
| Function | Chromatin remodeling cofactor |
| Modification | # |
| PMID for information on function | PMID:9663463 |
| Protein complex | # |
| Target molecule | histone |
| Target entity | H3K9me3, H3K36me3, H1.4K26me3 |
| Product | H3K9, H3K36, H1.4K26 |
| PMID for information on target | PMID:21757720 |
| Comment | The SKP1-Cul1-F-box and leucine-rich repeat protein 4 (SCF-FbxL4) ubiquitin ligase regulates lysine demethylase 4A (KDM4A)/Jumonji domain-containing 2A (JMJD2A) protein. The JMJD2/KDM43 histone demethylase family removes trimethylated H3K9, H3K36, and H1.4K26 . |
| Status of entry | # |
| Expression range: | 4.63 to 191.08 |
| Mean expression: | 44.53 ± 21.94 |
| Median expression: | 40.65 |