HGNC approved symbol | RPS6KA5 |
HGNC ID | HGNC:10434 |
HGNC approved name | ribosomal protein S6 kinase, 90kDa, polypeptide 5 |
Entrez gene ID | GeneID:9252 (SSTAR profile) |
UniProt AC (human) | O75582 |
UniProt ID (human) | KS6A5_HUMAN |
Pfam domains | Pkinase PF00069 (49-318, 426-687) Pkinase_C PF00433 (339-377) |
MGI symbol | Rps6ka5 |
MGI ID | MGI:1920336 |
UniProt AC (mouse) | Q8C050 |
UniProt ID (mouse) | KS6A5_MOUSE |
HGNC gene family tag | # |
HGNC gene family description | # |
Function | Histone modification write |
Modification | Histone phosphorylation |
PMID for information on function | PMID:12773393 |
Protein complex | # |
Target molecule | histone |
Target entity | H2AS1, H3S10, H3S28 |
Product | H2AS1ph, H3S10ph, H3S28ph |
PMID for information on target | PMID:12773393 |
Comment | The MSKs=(RPS6KA4, RPS6KA5), particularly MSK2, but not RSK2, are the major histone H3 and HMG-14 kinases. |
Status of entry | # |
Expression range: | 0.0 to 152.77 |
Mean expression: | 10.6 ± 16.07 |
Median expression: | 4.55 |