HGNC approved symbol | DZIP3 |
HGNC ID | HGNC:30938 |
HGNC approved name | DAZ interacting zinc finger protein 3 |
Entrez gene ID | GeneID:9666 (SSTAR profile) |
UniProt AC (human) | Q86Y13 |
UniProt ID (human) | DZIP3_HUMAN |
Pfam domains | TTC3_DZIP3_dom PF19179 (229-330) HEPN_DZIP3 PF18738 (421-546) zf-RING_2 PF13639 (1148-1188) |
MGI symbol | Dzip3 |
MGI ID | MGI:1917433 |
UniProt AC (mouse) | Q7TPV2 |
UniProt ID (mouse) | DZIP3_MOUSE |
HGNC gene family tag | RNF, PPP1R |
HGNC gene family description | RING-type (C3HC4) zinc fingers, Serine/threonine phosphatases / Protein phosphatase 1, regulatory subunits |
Function | Histone modification write |
Modification | Histone ubiquitination |
PMID for information on function | PMID:18206970 |
Protein complex | # |
Target molecule | histone, RNA |
Target entity | H2AK119 |
Product | H2AK119ub |
PMID for information on target | PMID:18206970 |
Comment | The N-CoR/HDAC1/3 complex specifically recruits a previously-unidentified specific histone H2A ubiquitin ligase, 2A-HUB/hRUL138 = DZIP3, to a subset of regulated gene promoters. |
Status of entry | # |
Expression range: | 0.0 to 150.03 |
Mean expression: | 10.71 ± 13.25 |
Median expression: | 6.92 |