HGNC approved symbol | HDAC4 |
HGNC ID | HGNC:14063 |
HGNC approved name | histone deacetylase 4 |
Entrez gene ID | GeneID:9759 (SSTAR profile) |
UniProt AC (human) | P56524 |
UniProt ID (human) | HDAC4_HUMAN |
Pfam domains | HDAC4_Gln PF12203 (63-153) Hist_deacetyl PF00850 (675-992) |
MGI symbol | Hdac4 |
MGI ID | MGI:3036234 |
UniProt AC (mouse) | Q6NZM9 |
UniProt ID (mouse) | HDAC4_MOUSE |
HGNC gene family tag | # |
HGNC gene family description | # |
Function | Histone modification erase |
Modification | Histone acetylation |
PMID for information on function | PMID:10220385 |
Protein complex | # |
Target molecule | histone |
Target entity | H2AKac, H2BKac, H3Kac, H4Kac |
Product | H2AK, H2BK, H3K, H4K |
PMID for information on target | PMID:10220385 |
Comment | HDAC1, HDAC4, HDAC5, and HDAC6 deacetylate all four core histones equally well, though deacetylation by HDAC4 and HDAC5 is incomplete. |
Status of entry | # |
Expression range: | 0.0 to 116.54 |
Mean expression: | 8.44 ± 7.94 |
Median expression: | 6.17 |