HGNC approved symbol | USP15 |
HGNC ID | HGNC:12613 |
HGNC approved name | ubiquitin specific peptidase 15 |
Entrez gene ID | GeneID:9958 (SSTAR profile) |
UniProt AC (human) | Q9Y4E8 |
UniProt ID (human) | UBP15_HUMAN |
Pfam domains | DUSP PF06337 (27-118) Ubiquitin_3 PF14836 (135-221) UCH PF00443 (289-930) USP7_C2 PF14533 (473-601) |
MGI symbol | Usp15 |
MGI ID | MGI:101857 |
UniProt AC (mouse) | Q8R5H1 |
UniProt ID (mouse) | UBP15_MOUSE |
HGNC gene family tag | USP |
HGNC gene family description | Ubiquitin-specific peptidases |
Function | Histone modification erase |
Modification | Histone ubiquitination |
PMID for information on function | PMID:24526689 |
Protein complex | # |
Target molecule | histone |
Target entity | H2BK120ub |
Product | H2BK120 |
PMID for information on target | PMID:24526689 |
Comment | Enhanced Usp15 binding to ubH2B facilitates deubiquitination of ubH2B in free histones but not in nucleosomes. |
Status of entry | # |
Expression range: | 0.0 to 1736.82 |
Mean expression: | 72.51 ± 139.02 |
Median expression: | 34.93 |