| HGNC approved symbol | HGNC ID | HGNC approved name | Entrez gene ID | UniProt AC (human) | UniProt ID (human) | Pfam domains | MGI symbol | MGI ID | UniProt AC (mouse) | UniProt ID (mouse) | HGNC gene family tag | HGNC gene family description | Function | Modification | PMID for information on function | Protein complex | Target molecule | Target entity | Product | PMID for information on target | Comment | Status of entry |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
ALKBH1
(details) |
17911 | alkB, alkylation repair homolog 1 (E. coli) | 8846 | Q13686 | ALKB1_HUMAN | 2OG-FeII_Oxy_2 PF13532 98-344 | Alkbh1 | 2384034 | P0CB42 | ALKB1_MOUSE | ALKB | Alkylation repair homologs | Histone modification | # | 22961808 | # | histone | H2A | # | # | ALKBH1 is a histone H2A dioxygenase involved in neural differentiation. | # |
|
ALKBH1
(details) |
17911 | Nucleic acid dioxygenase ALKBH1 (EC 1.14.11.-) (Alkylated DNA repair protein alkB homolog 1) (Alpha-ketoglutarate-dependent dioxygenase ABH1) (DNA 6mA demethylase) (DNA N6-methyl adenine demethylase ALKBH1) (EC 1.14.11.51) (DNA lyase ABH1) (EC 4.2.99.18) (DNA oxidative demethylase ALKBH1) (EC 1.14.11.33) (mRNA N(3)-methylcytidine demethylase) (EC 1.14.11.-) | 8846 | Q13686 | ALKB1_HUMAN | PF13532 | Alkbh1 | 2384034 | P0CB42 | ALKB1_MOUSE | ALKBH | Alkylation repair homologs | RNA modification, DNA modification | DNA demethylation, RNA demethylation | 18603530, 31188562, 18163532 | # | DNA, RNA | m3C, m1A of mRNA | C, A | 31188562, 30392959, 30017583 | Demethylates mRNAs containing N3-methylcytidine modification. Specifically demethylates DNA methylated on the 6th position of adenine (N6-methyladenosine) DNA. | New |