Protein complex info
Complex group nameSWI/SNF
Complex nameBAF
Status of entryUpdated
Genes in complexACTL6A#4, ACTL6B#5, ACTB#3, ARID1A#30, ARID1B#31, DPF3#174?, SMARCA2#560, SMARCA4#561, SMARCE1#571, SMARCC1#566, SMARCC2#567, SMARCB1#565, (SMARCD1#568|SMARCD2#569|SMARCD3#570)+
Alternative namesSWI/SNF-A
Proteins involved(ACTB), ARID1A, ARID1B/BAF250, SMARCA2, SMARCA4/BRG1/BAF190A, ACTL6A/BAF53, ACTL6B/BAF53B, SMARCE1/BAF57, SMARCC1/BAF155, SMARCC2/BAF170, SMARCB1/SNF5/INI1, and one or more of SMARCD1/BAF60A, SMARCD2/BAF60B, or SMARCD3/BAF60C. In muscle cells, the BAF complex also contains DPF3.
Uniprot IDs of involved proteins
ACL6A_HUMAN, ACL6B_HUMAN, ACTB_HUMAN, ARI1A_HUMAN, ARI1B_HUMAN, DPF3_HUMAN?, SMCA2_HUMAN, SMCA4_HUMAN, SMCE1_HUMAN, SMRC1_HUMAN, SMRC2_HUMAN, SNF5_HUMAN, (SMRD1_HUMAN|SMRD2_HUMAN|SMRD3_HUMAN)+
PMID for reference on complex composition10078207, 11078522
Functionchromatin remodeling complex
PMID for reference on function10078207
Target molecule typechromatin
Specific target#
Product#
Target UniProt ID#
PMID for reference on targets and products#
CommentIn muscle cells, the BAF complex also contains DPF3, which specifically binds acetylated lysines on histone 3 and 4 (H3K14ac, H3K9ac, H4K5ac, H4K8ac, H4K12ac, H4K16ac).